Article
The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros.
PLoS genetics - 1 Oct 2007
Wingert Rebecca A, Selleck Rori, Yu Jing, Song Huai-Dong, Chen Zhu, Song Anhua, Zhou Yi, Thisse Bernard, Thisse Christine, McMahon Andrew P, Davidson Alan J
Abstract excerpt
Kidney function depends on the nephron, which comprises a blood filter, a tubule that is subdivided into functionally distinct segments, and a collecting duct. How these regions arise during development is poorly understood. The zebrafish pronephros consists of two linear nephrons that develop from the intermediate mesoderm along the length of the trunk. Here we show that, contrary to current dogma, these...
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