Article
Serum carcinoembryonic antigen level is associated with epidermal growth factor receptor mutations in recurrent lung adenocarcinomas.
Cancer - 15 Dec 2007
Shoji Fumihiro, Yoshino Ichiro, Yano Tokujiro, Kometani Takuro, Ohba Taro, Kouso Hidenori, Takenaka Tomoyoshi, Miura Naoko, Okazaki Hiroshi, Maehara Yoshihiko
Abstract excerpt
BACKGROUND: The presence of epidermal growth factor receptor (EGFR) gene mutations is a good indicator of the clinical efficacy of gefitinib in patients with nonsmall cell lung cancer. It was recently reported that the serum carcinoembryonic antigen (CEA) level could be a predictive factor for the efficacy of gefitinib treatment; therefore, it is suggested that the EGFR gene mutation is associated with the serum...
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