Article
Comparison of strain-specific antibody responses during primary and secondary infections with respiratory syncytial virus.
Journal of medical virology - 1 Dec 2007
Scott Paul D, Ochola Rachel, Sande Charles, Ngama Mwanajuma, Okiro Emelda A, Medley Graham F, Nokes D James, Cane Patricia A
Abstract excerpt
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in infants. RSV repeatedly reinfects individuals: this may be due in part to the variability of the attachment (G) glycoprotein and changes in this protein have been shown to be under positive selection. Infants experiencing their primary infection show a genotype-specific antibody response with respect to the variable regions...
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