Article
Lactase persistence/non-persistence variants, C/T_13910 and G/A_22018, as a diagnostic tool for lactose intolerance in IBS patients.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2000
Bernardes-Silva Carlos Felipe, Pereira Alexandre C, de Fátima Alves da Mota Glória, Krieger José Eduardo, Laudanna Antonio Atílio
Abstract excerpt
BACKGROUND: Irritable bowel syndrome (IBS) is a symptom-based disorder characterized by abdominal pain related to altered bowel habit. We evaluated the predictive power of 2 genetic markers of hypolactasia, C/T_13910 and G/A_22018, in IBS patients with and without lactose intolerance in order to gain insight into the role of lactose intolerance in IBS. METHODS: Seventy five patients (59F/16M, mean age:...
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