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Expression of flagella is coincident with uropathogenic <i>Escherichia coli</i> ascension to the upper urinary tract

9 Oct 2007

Abstract excerpt

Uropathogenic Escherichia coli (UPEC) cause most uncomplicated urinary tract infections (UTIs) in humans. Because UTIs are considered to occur in an ascending manner, flagellum-mediated motility has been suggested to contribute to virulence by enabling UPEC to disseminate to the upper urinary tract. Previous studies from our laboratory and others have demonstrated a modest yet important role for flagella during...

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PMID: 17925449
DOI: 10.1073/pnas.0607898104

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