Article
A case report of myocardial infarction in young patient with a parental history of premature cardiovascular death: combination of prothrombotic gene mutations.
International journal of cardiology - 30 Oct 2008
Botto Nicoletta, Mariani Massimiliano, Manfredi Samantha, Andreassi Maria Grazia
Abstract excerpt
We report a case of myocardial infarction at a young age in a subject heterozygous for the G20210A prothrombin gene variant and homozygous for the C677T MTHFR polymorphism, who presented a strong family history of atherothrombosis. Genetic screening for inherited thrombophilia, especially in the presence of a strong familiarity, may be a critical information for secondary prevention of arterial thrombosis.
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