Article
Expression of the Rai (Shc C) adaptor protein in the human enteric nervous system.
Neurogastroenterology and motility - 1 Mar 2008
Villanacci V, Bassotti G, Ortensi B, Fisogni S, Cathomas G, Maurer C A, Galletti A, Salerni B, Pelicci G
Abstract excerpt
The adaptor protein Rai (ShcC/N-Shc) is almost exclusively present in the nervous system, although little is documented about its expression in the gut and the enteric nervous system (ENS). As Rai is a physiological substrate of Ret, an important factor for the development of ENS, we have evaluated the expression of Rai in the ENS in various segments of the human gastrointestinal tract. The expression of Rai was...
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