Article
Neurons and a subset of interstitial cells of Cajal in the enteric nervous system highly express Stam2 gene.
Anatomical record (Hoboken, N.J. : 2007) - 1 Jan 2012
Kapuralin Katarina, Van Ginneken Chris, Curlin Marija, Timmermans Jean-Pierre, Gajovic Srecko
Abstract excerpt
Signal transducing adaptor molecule 2 (STAM2) is a phosphotyrosine protein, which is a member of the endosomal sorting complex required for transport (ESCRT-0) and is involved in the sorting process of the mono-ubiquitinated endosomal cargo for degradation in the lysosome. Analysis of gene trap mice carrying lacZ in frame with Stam2 revealed beta-galactosidase activity in the enteric nervous system (both in the...
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