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Article

Identification of a Major Locus for Paget's Disease on Chromosome 10p13 in Families of British Descent

1 Oct 2007

Abstract excerpt

UNLABELLED: Mutations of SQSTM1 are an important cause of PDB, but other genes remain to be discovered. A major susceptibility locus for PDB was identified on chromosome 10p13 by a genome-wide linkage scan in families of British descent, which accounted for the vast majority of cases not caused by SQSTM1 mutations. INTRODUCTION: Paget's disease of bone (PDB) has a strong genetic component, and several...

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PMID: 17907922
DOI: 10.1359/jbmr.071004

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Related research

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Identification of a Major Locus for Paget's Disease on Chromosome 10p13 in Families of British DescentPMID 17907922Read ↗

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