Injection of Adeno-associated Viral Vector–Encoding Vascular Endothelial Growth Factor Gene in Infarcted Swine Myocardium: MR Measurements of Left Ventricular Function and Strain

Abstract excerpt

PURPOSE: To prospectively investigate the long-term effect of adeno-associated viral (AAV) vector-encoding vascular endothelial growth factor gene (VEGF) (AAV-VEGF) on left ventricular (LV) mass and volumes, as well as on regional contractility and circumferential strain, in a swine model of reperfused myocardial infarction. MATERIALS AND METHODS: All experimental procedures received approval from the...

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