Article
[Amyloidosis of the vitreous body. Possibilities of diagnosis].
Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft - 1 Jan 1991
Soltau J B, Seiberth V, Knorz M C, Liesenhoff H
Abstract excerpt
Vitreous amyloidosis is often the presenting clinical manifestation of type I, type II or Jewish-type familial amyloid polyneuropathy (FAP). FAP is an autosomal dominant inherited disorder. It is caused by systemic deposition of variants of transthyretin (TTR), formerly called prealbumin. TTR is a tetrameric protein with beta pleated sheets (mol wt = 56,000 dalton). In two cases we were able to confirm the...
Topics
- Aged
- Amyloidosis
- Diagnosis, Differential
- Eye Diseases
- Humans
- Male
- Middle Aged
- Mutation
- Vitrectomy
- Vitreous Body