Article
Ophthalmological manifestations in hereditary transthyretin (ATTR V30M) carriers: a review of 513 cases.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Jan 2015
Beirão João Melo, Malheiro Jorge, Lemos Carolina, Beirão Idalina, Costa Paulo, Torres Paulo
Abstract excerpt
PURPOSE: Assessment of ocular involvement in transthyretin-related familial amyloidosis with polyneuropathy (FAP) in a large cohort of Portuguese patients. METHODS: We reviewed the medical records of 513 Portuguese FAP mutation carriers, at the Ophthalmology Service, Centro Hospitalar do Porto, between 1 January 2008 and 31 January 2013. Abnormal conjunctiva vessels (ACV), Schirmer test, tear break-up time...
Topics
- Adult
- Amyloid Neuropathies, Familial
- Cross-Sectional Studies
- Female
- Humans
- Male
- Middle Aged
- Mutation
- Portugal
- Prealbumin
- Prevalence