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Article

A three-dimensional model of mammalian tyrosinase active site accounting for loss of function mutations.

Pigment cell research - 1 Oct 2007

Schweikardt Thorsten, Olivares Concepción, Solano Francisco, Jaenicke Elmar, García-Borrón José Carlos, Decker Heinz

Abstract excerpt

Tyrosinases are the first and rate-limiting enzymes in the synthesis of melanin pigments responsible for colouring hair, skin and eyes. Mutation of tyrosinases often decreases melanin production resulting in albinism, but the effects are not always understood at the molecular level. Homology mode...

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PMID: 17850513
DOI: 10.1111/j.1600-0749.2007.00405.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17850513-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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