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Article

MicroRNA regulation of cyclooxygenase-2 during embryo implantation

11 Sept 2007

Abstract excerpt

The implantation process is complex, requiring reciprocal interactions between implantation-competent blastocysts and the receptive uterus. Because microRNAs (miRNAs) have major roles in regulating gene expression, we speculated that they participate in directing the highly regulated spatiotemporally expressed genetic network during implantation. Here, we show that two miRNAs, mmu-miR-101a and mmu-miR-199a*, are...

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PMID: 17848513
DOI: 10.1073/pnas.0705917104

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