Autosomal mutations and human spermatogenic failure.

Abstract excerpt

Infertility, defined as the inability to conceive after 1 year of unprotected intercourse, is a healthcare problem that has a worldwide impact. Male factors are involved in at least half of these cases of infertility. Despite 3 years of assisted reproductive activities, a considerable number of cases (25-30%) remain idiopathic. This situation can be explained by a poor understanding of the basic mechanisms...

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