Article
B cells control the aggregability of CD4 on T cells through continuous physical interactions.
Immunology - 1 Dec 1991
Mecheri S, Dannecker G, Dennig D, Hoffmann M K
Abstract excerpt
It has previously been demonstrated that a gene on chromosome 1 in or near Mls-1 controls, on the surface of B cells, the mobility and aggregability of major histocompatibility complex (MHC) class II molecules but not the mobility or aggregability of other B-cell molecules, such as immunoglobulin (Ig) and class I antigens. We report here that this gene may also influence the aggregability of two class II...
Topics
- Animals
- B-Lymphocytes
- CD4 Antigens
- Cells, Cultured
- Genotype
- Histocompatibility Antigens Class II
- Lymphocyte Cooperation
- Mice
- Mice, Inbred Strains
- Minor Lymphocyte Stimulatory Loci
- Spleen
