Article
Single nucleotide polymorphisms in ABCG5 and ABCG8 are associated with changes in cholesterol metabolism during weight loss.
Journal of lipid research - 1 Dec 2007
Santosa Sylvia, Demonty Isabelle, Lichtenstein Alice H, Ordovas Jose M, Jones Peter J H
Abstract excerpt
The purpose of this study was to examine whether changes in cholesterol metabolism after weight loss were affected by single nucleotide polymorphisms (SNPs) in ABCG5 and ABCG8 genes. Thirty-five hypercholesterolemic women lost 11.7 +/- 2.5 kg (P < 0.001). Cholesterol kinetics were assessed using...
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