Article
[Molecular background and clinical characteristics of autosomal dominant type 2 diabetes mellitus].
Przeglad lekarski - 1 Jan 2000
Małecki M, Krolewski A S
Abstract excerpt
Type 2 diabetes is a complex disease and genetic as well as environmental factors play a role in its pathogenesis. Six different genes have been identified so far to be responsible for rare forms of autosomal dominant, early onset type 2 diabetes mellitus. All but one are transcription factors which influence expression of the other genes through the regulation of mRNA synthesis. These are hepatocyte nuclear...
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