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Article

The identification of two CYP17 alleles in the South African Angora goat.

Drug metabolism reviews - 1 Jan 2007

Storbeck Karl-Heinz, Swart Amanda C, Slabbert Johannes T, Swart Pieter

Abstract excerpt

South African Angora goats (Capra hircus) are susceptible to cold stress, due to the inability of the adrenal cortex to produce sufficient levels of cortisol. Two CYP17 isoforms were identified, cloned and characterized in this study. Sequence analysis revealed three amino acid differences between the two CYP17 isoforms, which resulted in a significant difference in 17,20 lyase activity of the expressed enzymes...

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PMID: 17786633
DOI: 10.1080/03602530701468649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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