Article
Systems level circuit model of C. elegans undulatory locomotion: mathematical modeling and molecular genetics.
Journal of computational neuroscience - 1 Jun 2008
Karbowski Jan, Schindelman Gary, Cronin Christopher J, Seah Adeline, Sternberg Paul W
Abstract excerpt
To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular, we quantitatively analyzed the motion of C. elegans with defective synaptic GABA and acetylcholine transmission, defective muscle calcium signaling, and defective muscles and cuticle structures, and compared the data with our systems...
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