Article
Nanomechanical properties of glucans and associated cell-surface adhesion of Streptococcus mutans probed by atomic force microscopy under in situ conditions.
Microbiology (Reading, England) - 1 Sept 2007
Cross Sarah E, Kreth Jens, Zhu Lin, Sullivan Richard, Shi Wenyuan, Qi Fengxia, Gimzewski James K
Abstract excerpt
This study used atomic force microscopy (AFM) to probe the local cell-surface interactions associated with the glucan polymers of Streptococcus mutans, the macromolecules most commonly attributed to the virulence of this microbe. In situ force spectroscopy was used to quantitatively probe and correlate cell-surface adhesion and dynamics with S. mutans UA140 wild-type and five glucosyltransferase mutants. Adhesion...
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