Article
Association of kallikrein gene polymorphisms with intracranial aneurysms.
Stroke - 1 Oct 2007
Weinsheimer Shantel, Goddard Katrina A B, Parrado Antonio R, Lu Qing, Sinha Moumita, Lebedeva Elena R, Ronkainen Antti, Niemelä Mika, Khusnutdinova Elza K, Khusainova Rita I, Helin Katariina, Jääskeläinen Juha E, Sakovich Vladimir P, Land Susan, Kuivaniemi Helena, Tromp Gerard
Abstract excerpt
BACKGROUND AND PURPOSE: Genomewide DNA linkage analysis identified a susceptibility locus for intracranial aneurysm (IA) on chromosome 19q13 in the Finnish population, a region including the kallikrein gene cluster. We investigated the association of single nucleotide polymorphisms (SNPs) in the kallikrein gene cluster with IA in the Finnish population. METHODS: We genotyped 18 haplotype-tagging SNPs spanning a...
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