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Article

Inhibition of primordial germ cell proliferation by the medaka male determining gene Dmrt I bY.

BMC developmental biology - 30 Aug 2007

Herpin Amaury, Schindler Detlev, Kraiss Anita, Hornung Ute, Winkler Christoph, Schartl Manfred

Abstract excerpt

BACKGROUND: Dmrt I is a highly conserved gene involved in the determination and early differentiation phase of the primordial gonad in vertebrates. In the fish medaka dmrt I bY, a functional duplicate of the autosomal dmrt I a gene on the Y-chromosome, has been shown to be the master regulator of male gonadal development, comparable to Sry in mammals. In males mRNA and protein expression was observed before...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17760954
DOI: 10.1186/1471-213X-7-99
PMCID: PMC2034567

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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