Article
[A new pleiotropic mutation affecting purine metabolism, sporulation and biosynthesis of exoenzymes in Bacillus subtilis].
Genetika - 1 Jun 1991
Maznitsa I I, Nudler A A, Burd G I
Abstract excerpt
A pleiotropic mutation (cpm) which is localised in the vicinity of the spoA gene of Bacillus subtilis chromosome has been described. The mutation inhibits spore formation, renders bacteria auxotrophic for adenine and tyrosine, increases sensitivity to antibiotics, decreases cell motility and the ability to grow on D-ribose and D-xylose, inhibits growth of bacteriophages PBS1 and AR9 as well as enhances activity...
Topics
- 5'-Nucleotidase
- Adenylosuccinate Synthase
- Bacillus subtilis
- Inosine
- Mutation
- Phenotype
- Purine-Nucleoside Phosphorylase
- Purines
- Selection, Genetic
- Spores
- Transduction, Genetic