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Article

Genetic modulation of cognitive flexibility and socioemotional behavior in rhesus monkeys

21 Aug 2007

Abstract excerpt

In human and nonhuman primates, structural variants of the gene encoding the serotonin transporter [5-hydroxytryptamine transporter (5-HTT)] affect the transcription and functional efficacy of 5-HTT. Prior work has shown that structural variants differentially affect function of the amygdala and ventromedial prefrontal cortex (VMPFC), regions important for the regulation and expression of emotion. However,...

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PMID: 17715054
DOI: 10.1073/pnas.0706583104

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