Article
Cognitive impact of genetic variation of the serotonin transporter in primates is associated with differences in brain morphology rather than serotonin neurotransmission.
Molecular psychiatry - 1 May 2010
Jedema H P, Gianaros P J, Greer P J, Kerr D D, Liu S, Higley J D, Suomi S J, Olsen A S, Porter J N, Lopresti B J, Hariri A R, Bradberry C W
Abstract excerpt
A powerful convergence of genetics, neuroimaging and epidemiological research has identified the biological pathways mediating individual differences in complex behavioral processes and the related risk for disease. Orthologous genetic variation in non-human primates (NHPs) represents a unique opportunity to characterize the detailed molecular and cellular mechanisms that bias behaviorally and clinically relevant...
Topics
- Animals
- Avoidance Learning
- Behavior, Animal
- Benzylamines
- Brain
- Brain Mapping
- Carbon Isotopes
- Choice Behavior
- Cognition
- Genotype