Article
Genome-wide polysomal analysis of a yeast strain with mutated ribosomal protein S9.
BMC genomics - 21 Aug 2007
Pnueli Lilach, Arava Yoav
Abstract excerpt
BACKGROUND: The yeast ribosomal protein S9 (S9) is located at the entrance tunnel of the mRNA into the ribosome. It is known to play a role in accurate decoding and its bacterial homolog (S4) has recently been shown to be involved in opening RNA duplexes. Here we examined the effects of changing the C terminus of S9, which is rich in acidic amino acids and extends out of the ribosome surface. RESULTS: We...
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