Article
A fast method to detect cell surface expression of thyrotropin receptor (TSHr): the microchip flow cytometry analysis.
Thyroid : official journal of the American Thyroid Association - 1 Sept 2007
Agretti Patrizia, De Marco Giuseppina, Capodanno Alessandra, Ferrarini Eleonora, Dimida Antonio, Sansone Daniela, Collecchi Paola, Pinchera Aldo, Vitti Paolo, Tonacchera Massimo
Abstract excerpt
Loss-of-function mutations of the thyrotropin receptor (TSHr) may be responsible for congenital hypothyroidism or isolated hyperthyreotropinemia. To study cell surface expression of inactivating TSHr mutations detected in patients with isolated hyperthyreotropinemia (L252P, Q8fsX62, P27T, E34K, R...
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