Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

hDectin-1 is involved in uptake and cross-presentation of cellular antigens.

Blood - 15 Apr 2008

Weck Markus M, Appel Silke, Werth Daniela, Sinzger Christian, Bringmann Anita, Grünebach Frank, Brossart Peter

Abstract excerpt

Human Dectin-1 (hDectin-1) is a member of the C-type lectin-like receptor family that was shown to be the major receptor for fungal beta-glucans and to play an important role in the cellular responses mediated by these carbohydrates. In this study, we demonstrate that hDectin-1 is involved in the uptake and cross-presentation of cellular antigens. Furthermore, activation of monocyte-derived dendritic cells (MDCs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Chromium
Share to Cytomegalovirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-A2 Antigen

Share to Lectins, C-Type

Share to Phagocytosis

Share to T-Lymphocytes, Cytotoxic

Share to Toll-Like Receptors

Source

Identifiers

PMID: 17698636
DOI: 10.1182/blood-2006-10-051375

Genes

TLR2
TLR3
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

hDectin-1 is involved in uptake and cross-presentation of cellular antigens.PMID 17698636Read ↗

The Biological Role of Dectin-1 in Immune ResponseSemantic proximity Read ↗

CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.Semantic proximity Read ↗

β‐glucan recognition by the innate immune systemSemantic proximity Read ↗

Dectin-1 is required for beta-glucan recognition and control of fungal infection.Semantic proximity Read ↗

Galectin-3 as a modifier of anti-microbial immunity: Unraveling the unknownsSemantic proximity Read ↗

Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2Semantic proximity Read ↗

Upregulation of type 1 conventional dendritic cells implicates antigen cross-presentation in multisystem inflammatory syndromeSemantic proximity Read ↗

Functions of galectins as ‘self/non-self’-recognition and effector factorsSemantic proximity Read ↗

Antigen Cross-Presentation of Immune ComplexesSemantic proximity Read ↗

Conveying glycan information into T‐cell homeostatic programs: a challenging role for galectin‐1 in inflammatory and tumor microenvironmentsSemantic proximity Read ↗

Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responsesSemantic proximity Read ↗

The exploitation of distinct recognition receptors in dendritic cells determines the full range of host immune relationships with Candida albicansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.