Article
C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1.
Neuron - 16 Aug 2007
Grill Brock, Bienvenut Willy V, Brown Heather M, Ackley Brian D, Quadroni Manfredo, Jin Yishi
Abstract excerpt
C. elegans RPM-1 (for Regulator of Presynaptic Morphology) is a member of a conserved protein family that includes Drosophila Highwire and mammalian Pam and Phr1. These are large proteins recently shown to regulate synaptogenesis through E3 ubiquitin ligase activities. Here, we report the identif...
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