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Dissecting in vitro host cell infection by Plasmodium sporozoites using flow cytometry

14 Aug 2007

Abstract excerpt

The study of the liver stage of malaria has been hampered by limitations in the experimental approaches required to effectively dissect and quantify hepatocyte infection by Plasmodium. Here, we report on the use of flow cytometry, in conjunction with GFP-expressing Plasmodium sporozoites, to assess the various steps that constitute a successful malaria liver infection: cell traversal, hepatocyte invasion and...

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PMID: 17697130
DOI: 10.1111/j.1462-5822.2007.01032.x

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