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Article

Migration of <i>Plasmodium</i> Sporozoites Through Cells Before Infection

5 Jan 2001

Abstract excerpt

Intracellular bacteria and parasites typically invade host cells through the formation of an internalization vacuole around the invading pathogen. Plasmodium sporozoites, the infective stage of the malaria parasite transmitted by mosquitoes, have an alternative mechanism to enter cells. We observed breaching of the plasma membrane of the host cell followed by rapid repair. This mode of entry did not result in the...

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Identifiers

PMID: 11141568
DOI: 10.1126/science.291.5501.141

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