Article
A Darwinian approach to Huntington's disease: subtle health benefits of a neurological disorder.
Medical hypotheses - 1 Jan 2007
Eskenazi Benjamin R, Wilson-Rich Noah S, Starks Philip T
Abstract excerpt
Huntington's disease (HD) is a neurodegenerative disorder that, unlike most autosomal dominant disorders, is not being selected against. One explanation for the maintenance of the mutant HD allele is that it is transparent to natural selection because disease symptoms typically occur subsequent to an individual's peak reproductive years. While true, this observation does not explain the population-level increase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
