Article
BRAF V600E mutation and p27 kip1 expression in papillary carcinomas of the thyroid <or=1 cm and their paired lymph node metastases.
Cancer - 15 Sept 2007
Rodolico Vito, Cabibi Daniela, Pizzolanti Giuseppe, Richiusa Pierina, Gebbia Nicola, Martorana Anna, Russo Antonio, Amato Marco C, Galluzzo Aldo, Giordano Carla
Abstract excerpt
BACKGROUND: BRAF(V600E) mutation and p27(kip1) expression have been introduced as novel indicators that may predict prognosis in different tumors, as well as in papillary thyroid carcinomas. METHODS: Tissue samples from 214 consecutive patients who underwent total or near-total thyroidectomy with histological diagnosis of papillary thyroid carcinoma (PTC) <or=1 cm were analyzed for BRAF(V600E) mutation by a...
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