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Article

Porphyromonas gingivalis selectively up-regulates the HIV-1 coreceptor CCR5 in oral keratinocytes.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2007

Giacaman Rodrigo A, Nobbs Angela H, Ross Karen F, Herzberg Mark C

Abstract excerpt

Primary infection of oral epithelial cells by HIV-1, if it occurs, could promote systemic infection. Most primary systemic infections are associated with R5-type HIV-1 targeting the R5-specific coreceptor CCR5, which is not usually expressed on oral keratinocytes. Because coinfection with other microbes has been suggested to modulate cellular infection by HIV-1, we hypothesized that oral keratinocytes may...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, PAR-1

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Source

Identifiers

PMID: 17675516
DOI: 10.4049/jimmunol.179.4.2542

Genes

CCR5
CXCR4
TERT
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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