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Article

Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV

5 Jun 2018

Abstract excerpt

The association between mucosal microbiota and HIV-1 infection has garnered great attention in the field of HIV-1 research. Previously, we reported a receptor-independent HIV-1 entry into epithelial cells mediated by a Gram-negative invasive bacterium, Porphyromonas gingivalis. Here, we present evidence showing that P. gingivalis outer membrane vesicles (OMVs) promote mucosal transmission of HIV-1. We...

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PMID: 29891956
DOI: 10.1038/s41598-018-27284-6

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