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Article

Immune-like phagocyte activity in the social amoeba.

Science (New York, N.Y.) - 3 Aug 2007

Chen Guokai, Zhuchenko Olga, Kuspa Adam

Abstract excerpt

Social amoebae feed on bacteria in the soil but aggregate when starved to form a migrating slug. We describe a previously unknown cell type in the social amoeba, which appears to provide detoxification and immune-like functions and which we term sentinel (S) cells. S cells were observed to engulf bacteria and sequester toxins while circulating within the slug, eventually being sloughed off. A Toll/interleukin-1...

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Identifiers

PMID: 17673666
DOI: 10.1126/science.1143991
PMCID: PMC3291017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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