Article
Cyclin-dependent kinase 4 (CDK4) expression in pancreatic endocrine tumors.
Neuroendocrinology - 1 Jan 2007
Lindberg Daniel, Hessman Ola, Akerström Göran, Westin Gunnar
Abstract excerpt
BACKGROUND/AIMS: Pancreatic endocrine tumors (PETs) occur sporadically, in association with the multiple endocrine neoplasia type 1 (MEN1) and the von Hippel-Lindau syndromes. CDK4 is central to the cell cycle control in pancreatic beta cells, and we have assessed whether CDK4 expression is deregulated in 18 human sporadic or familial PETs. METHODS: Real-time quantitative PCR, immunohistochemistry, DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
