Article
Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders.
Psychiatry research - 30 Sept 2007
Pae Chi-Un, Yoon Soo-Jung, Patkar Ashwin A, Kim Jung-Jin, Lee Chul, Paik In-Ho
Abstract excerpt
Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n=61; patients with bipolar I disorder, n=80; control, n=106) was carried out using PCR-based techniques. These preliminary results showed...
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