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Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcome

17 Jul 2007

Abstract excerpt

Cutaneous T-cell lymphoma (CTCL) is defined by infiltration of activated and malignant T cells in the skin. The clinical manifestations and prognosis in CTCL are highly variable. In this study, we hypothesized that gene expression analysis in lesional skin biopsies can improve understanding of the disease and its management. Based on 63 skin samples, we performed consensus clustering, revealing 3 patient...

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PMID: 17638852
DOI: 10.1182/blood-2006-12-061507

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