Neural stemness contributes to cell tumorigenicity

Abstract excerpt

BACKGROUND: Previous studies demonstrated the dependence of cancer on nerve. Recently, a growing number of studies reveal that cancer cells share the property and regulatory network with neural stem/progenitor cells. However, relationship between the property of neural stemness and cell tumorigenicity is unknown. RESULTS: We show that neural stem/progenitor cells, but not non-neural embryonic or somatic...

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