Article
Colon cancer metastasis in mouse liver is not affected by hypercoagulability due to Factor V Leiden mutation.
Journal of cellular and molecular medicine - 1 Jan 2000
Klerk C P W, Smorenburg S M, Spek C A, Van Noorden C J F
Abstract excerpt
Clinical trials have shown life-prolonging effects of antithrombotics in cancer patients, but the molecular mechanisms remain unknown due to the multitude of their effects. We investigated in a mouse model whether one of the targets of antithrombotic therapy, fibrin deposition, stimulates tumour...
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