Article
A di-leucine sorting signal in ZIP1 (SLC39A1) mediates endocytosis of the protein.
The FEBS journal - 1 Aug 2007
Huang Liping, Kirschke Catherine P
Abstract excerpt
It has been demonstrated that the plasma membrane expression of ZIP1 is regulated by endocytic mechanisms. In the zinc-replete condition, the level of surface expressed ZIP1 is low due to the rapid internalization of ZIP1. The present study aimed to identify a sorting signal(s) in ZIP1 that media...
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