Article
The uncoupling protein-1 gene -3826A/G polymorphism and hypertension in Japanese subjects.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Kotani Kazuhiko, Sakane Naoki, Saiga Kyoko, Tsuzaki Kokoro, Shimohiro Hisashi, Tabata Masahiko, Kurozawa Youichi
Abstract excerpt
BACKGROUND: The possible effects of the uncoupling protein-1 (UCP-1) gene -3826A/G polymorphism on hypertension (HT) have yet to be elucidated. METHODS: A total of 578 Japanese subjects (231 males and 347 females, mean age 58.4 years) were enrolled in the study to investigate the association between HT and the -3826A/G polymorphism by genomic PCR and Bcl1-restriction fragment length polymorphism methods. RESULTS:...
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