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Article

No association of spastic paraparesis genes in PSEN1 Alzheimer's disease with spastic paraparesis.

Neuroreport - 6 Aug 2007

Karlstrom Helena, Kwok John B J, Gregory Gillian C, Hallupp Marianne, Brooks William S, Schofield Peter R

Abstract excerpt

Familial Alzheimer's disease due to presenilin 1 (PSEN1) mutations shows considerable phenotypic variability with differences in neuropathology and neurological symptoms. Spastic paraparesis is a common neurological phenotype associated with Alzheimer's disease arising from PSEN1 mutations. To in...

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Source

Identifiers

PMID: 17632280
DOI: 10.1097/WNR.0b013e3282405209

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17632280-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Clinical and Molecular Findings in a Turkish Family Who Had a (c.869- 1G>A) Splicing Variant in PSEN1 Gene with A Rare Condition: The Variant Alzheimer's Disease with Spastic Paraparesis.Semantic proximity Read ↗

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