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Lucentamycins A−D, Cytotoxic Peptides from the Marine-Derived Actinomycete <i>Nocardiopsis </i><i>lucentensis</i>

14 Jul 2007

Abstract excerpt

Four new 3-methyl-4-ethylideneproline-containing peptides, lucentamycins A-D (1-4), have been isolated from the fermentation broth of a marine-derived actinomycete identified by phylogenetic methods as Nocardiopsis lucentensis (strain CNR-712). The planar structures of the new compounds were assigned on the basis of 1D and 2D NMR spectroscopic techniques, while the absolute configurations of the amino acid...

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PMID: 17630797
DOI: 10.1021/np070101b

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