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Article

alpha-Synuclein gene duplication is present in sporadic Parkinson disease.

Neurology - 1 Jan 2008

Ahn T-B, Kim S Y, Kim J Y, Park S-S, Lee D S, Min H J, Kim Y K, Kim S E, Kim J-M, Kim H-J, Cho J, Jeon B S

Abstract excerpt

OBJECTIVE: alpha-Synuclein gene (SNCA) multiplication was found in familial Parkinson disease (PD). We examined SNCA multiplication in patients with familial and sporadic PD and multiple system atrophy (MSA). METHODS: We screened 1,106 patients with parkinsonism (PD = 906, MSA = 200) for SNCA multiplication by multiplex PCR. Fluorescent in situ hybridization was done to confirm the multiplication....

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Identifiers

PMID: 17625105
DOI: 10.1212/01.wnl.0000271080.53272.c7

Genes

SNCA
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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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