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Article

JAM-C regulates unidirectional monocyte transendothelial migration in inflammation.

Blood - 1 Oct 2007

Bradfield Paul F, Scheiermann Christoph, Nourshargh Sussan, Ody Christiane, Luscinskas Francis W, Rainger G Ed, Nash Gerard B, Miljkovic-Licina Marijana, Aurrand-Lions Michel, Imhof Beat A

Abstract excerpt

Monocyte recruitment from the vasculature involves sequential engagement of multiple receptors, culminating in transendothelial migration and extravasation. Junctional adhesion molecule-C (JAM-C) is localized at endothelial intercellular junctions and plays a role in monocyte transmigration. Here, we show that blockade of JAM-B/-C interaction reduced monocyte numbers in the extravascular compartment through...

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Source

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Identifiers

PMID: 17625065
DOI: 10.1182/blood-2007-03-078733
PMCID: PMC1988941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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