Article
Hereditary breast cancer: pathobiology, clinical translation, and potential for targeted cancer therapeutics.
Familial cancer - 1 Jan 2008
Rubinstein Wendy S
Abstract excerpt
BRCA1 and BRCA2 breast cancers have distinct biological features as evidenced by histopathologic, immunohistochemical, gene expression profiling, and array-comparative genomic hybridization data. BRCA1 breast cancers may have a worse prognosis but may, however be amenable to treatment such as che...
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