Article
Ambra1 regulates autophagy and development of the nervous system.
Nature - 28 Jun 2007
Fimia Gian Maria, Stoykova Anastassia, Romagnoli Alessandra, Giunta Luigi, Di Bartolomeo Sabrina, Nardacci Roberta, Corazzari Marco, Fuoco Claudia, Ucar Ahmet, Schwartz Peter, Gruss Peter, Piacentini Mauro, Chowdhury Kamal, Cecconi Francesco
Abstract excerpt
Autophagy is a self-degradative process involved both in basal turnover of cellular components and in response to nutrient starvation or organelle damage in a wide range of eukaryotes. During autophagy, portions of the cytoplasm are sequestered by double-membraned vesicles called autophagosomes,...
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